- To increase knowledge, improve clinical practice and healthcare delivery, and promote clinical research, including biological monitoring, for patients with autoimmune and auto-inflammatory diseases treated with bone marrow transplant or other stem cell therapies in France.
- Provide patients and patient organizations with accessible updated scientific information on the indications and best clinical practice standards for stem cell therapy in the treatment of autoimmune diseases
- Host the National MATHEC Multidisciplinary Consultation Meeting (RCP MATHEC) for stem cell therapy health care professionals who treat patients with autoimmune diseases, via telephone or video conferencing. The purpose of the meeting is to validate by consensus the indications for stem cell therapy in patients with autoimmune diseases (Scleroderma, Lupus, Multiple Sclerosis, Peripheral chronic neuropathies, Inflammatory diseases of the digestive tract, other …), according to the model used for rare cancers (INCa Cancer Plan) and for rare diseases (orphanet, PNMR3).
- Provide healthcare professionals with standardized protocols for multidisciplinary care according to validated procedures that meet French and European standards (JACIE accreditation), and which have been implemented in centers accredited for the practice of bone marrow transplantation and stem cell therapy in autoimmune diseases. This ensures a standardization of patient care across centers, facilitates a multidisciplinary approach that combines the different competencies of stem cell therapy experts, and promotes the implementation of the European or International clinical practice guidelines for the treatment and follow-up of patients according to the standards required for stem cell therapy.
- To facilitate, the combined clinical (databases) and biological (biobanks) collection of patient data necessary for the monitoring of stem cell therapy and autoimmune diseases, using a common registry, in collaboration with the SFGM-TC and the EBMT. The registry is accessible online to each center, and collected data are shared across sites.